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Human Adipose-derived Stem Cells – Adult Female

$749.00

Human adipose-derived stem cells (hADSC) isolated from adult female adipose tissue; cryopreserved.

1 x 106 cells

Cells produced upon request

 

Please see our statement on why passage numbers can be misleading.

Human adipose-derived stem cells (hADSC) are multipotent cells with a high capacity for expansion and are ideal for regenerative therapy applications. Human adipose tissue-derived stem cells demonstrate phenotypic and functional characteristics similar to those found in human bone marrow-derived mesenchymal stem cells (hBM-MSC) and can differentiate in vitro into specialized cells of the body such as chondrocytes, osteocytes, adipocytes, neural cells, endothelial cells, myocytes, and hepatocytes. Their easy accessibility, low immunogenicity and their ability to secrete trophic factors, cytokines and chemokines make hADSC a favorable cell type for experimental and clinical use. Adipose-derived adult stem cells are also demonstrated to have proangiogenic, immunomodulatory, anti-apoptotic, anti-inflammatory, and anti-scarring effects. Many trials are underway to understand the potential of these cells to be used for a wide range of clinical conditions including skeletal tissue repair, ischemic injuries, myocardial infarction, soft tissue regeneration and immune disorders such as lupus, arthritis, Crohn’s disease, multiple sclerosis, diabetes mellitus, and graft-versus-host disease.

Human adipose derived stem cells are isolated from adult female (single donor) lipoaspirates collected during elective surgical liposuction procedures. Cells are cultured, passaged for purity, cryopreserved, and delivered frozen. Each vial contains 1 x 106 cells in 1 mL volume. Our human adipose mesenchymal stem cells are characterized by flow cytometry and are negative for mycoplasma, yeast, fungi, and bacteria. HIV-1, HIV-2, and HBV are not detected. A certificate of analysis (CoA) is provided with each vial purchased. Additional donor information may be available when you place your order. Cells are assured to further culture using the protocol provided by JangoCell.

Adipose-derived stem cells (ADSC) are also known as: AD-MSC, ADMSC, ASC, ASCS, adipose-derived mesenchymal stem cells, fat stem cells, adipose-derived MSC, adipose-derived adult stem cells, adipose-derived stromal cells, and adipose stem cells.

Product Use

This cell product is intended for laboratory research purposes only. Not approved for use in human subjects or for clinical, diagnostic, or therapeutic use in animals or humans. 

Human Material Precaution

Tissues used for cell isolation were acquired with informed consent and adhere to HIPAA standards for human privacy protection. All human biological material, including human cells, should always be handled as potentially infectious using at least Biosafety Level 2 precautions; we recommend that appropriate safety procedures be followed, using the same biosafety protocol used with known infectious material. Viral testing cannot prove the absence of a latent viral genome.

 

Note: Image shown is representative of the cell product described but may not show the actual purchased product.

Additional information

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JangoCell Statement on Passage Number

While passage number is the de facto metric used for determining cell proliferation capacity, the actual capacity is dependent upon the total number of cell divisions (or population doubling number (PDN)) that a particular cell type can undergo. This can be illustrated with a simple example. Since stem cells are typically passaged upon reaching confluence, cells grown at low confluence in a flask or in a large vessel such as a bioreactor (large surface area to cell number) will require many more doublings to reach confluence before they are ‘passaged’ than cells seeded at high confluence. This can result in low passage numbers, but a cell population with more limited capacity for further cell division. Therefore, passage number is not the most reliable means of determining future cell proliferation capacity after purchase.

For these reasons, and to provide transparency concerning our cell products, JangoCell will express future cell division capacity, or the number of times that our cells will be able to divide and double in number after purchase (after thaw), in terms of population doubling number (PDN). We will express the current cell division number, or the number of times that our cells have already divided and doubled in number before cryopreservation, in terms of population doubling level (PDL). JangoCell’s primary stem cells when plated at ~20% confluency will display a PDN between 30-40 when cultured using the protocol recommended by JangoCell for each specific cell type.

Please see our page on passage number under Technical Resources for more information.

Catalog Number ADSC-HF-02
Lot Number Included with shipment
Country of Manufacture USA
Quantity 1 x 106 cells/vial
Storage Immediately transfer cells from dry ice to liquid nitrogen upon arrival.
Shipping Info Dry ice; Overnight shipping
Also Known As AD-MSC, ADMSC, ASC, ASCS, adipose-derived mesenchymal stem cells, fat stem cells, adipose-derived MSC, adipose-derived adult stem cells, adipose-derived stromal cells, and adipose stem cells.
Product Use This cell product is intended for laboratory research purposes only. Not approved for use in human subjects or for clinical, diagnostic, or therapeutic use in animals or humans.
References Frese L, Dijkman PE and Hoerstrup SP. Adipose tissue-derived stem cells in regenerative medicine. Transfusion Medicine and Hemotherapy. 2016; 43: 268–274.

Bateman ME, Strong AL, Gimble JM and Bunnell BA. Concise Review: Using Fat to Fight Disease: A systematic review of nonhomologous adipose-derived stromal/stem cell therapies. Stem Cells. 2018; 36:1311-1328. doi: 10.1002/stem.2847. Epub 2018 Jul 16.

Bertolini F, Lohsiriwat V, Petit JY and Kolonin MG. Adipose tissue cells, lipotransfer and cancer: A challenge for scientists, oncologists and surgeons. Biochimica et Biophysica Acta. 2012; 1826:209–214.

http://clinicaltrials.gov, 2016.

Contact us for the technical documents on this product.

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