Human Peripheral Blood Mononuclear Cells – Adult Male

$499.00

Human peripheral blood mononuclear cells (PBMCs) isolated from adult male whole blood; cryopreserved.

100 x 106 cells

Cells produced upon request

SKU PBMC-HM-02 Categories , Tags , , , , ,

Human peripheral blood mononuclear cells (hPBMCs) are critical components of the innate and adaptive immune response and are useful tools for in-vitro and ex-vivo immunoassays, cytotoxicity and infectious disease studies, cancer research, and in drug development and discovery.

We isolate adult male (single donor) PBMCs from whole blood using Ficoll and density gradient centrifugation, and provide a cryopreserved, highly purified subset of these cell populations. Each unit of blood is tested for the standard FDA-required viral markers, and found negative for HbsAg, HIV-1/2 Ab, HCV Ab, HIV/HBV/HCV NAT, Syphilis (RPR), WNV NAT, and Zika NAT using FDA-approved methods. Our human peripheral blood mononuclear cells are negative for mycoplasma, fungi, and bacteria. Human PBMCs are characterized by flow cytometry; a certificate of analysis (CoA) is provided with each lot purchased.

Available fresh or frozen upon request. Frozen cells are cryopreserved in animal component-free CryoStor® CS10. Custom quantities available; choice of anticoagulant when order is placed. JangoCell’s adult male PBMC are collected from qualified, traceable donors; additional donor information may be available when you place your order. Custom options include choice of gender, age, race, HLA typing, smoking status, and disease state.

Peripheral blood mononuclear cells (PBMCs) are also known as: Blood cells, immune cells, PBMC cells, mononuclear cells from peripheral blood, MNC-PB, peripheral mononuclear cells, PMNCs, mononuclear cells, and MNCs.

Product Use

This cell product is intended for laboratory research purposes only. Not approved for use in human subjects or for clinical, diagnostic, or therapeutic use in animals or humans.

Human Material Precaution

Tissues used for cell isolation were acquired with informed consent and adhere to HIPAA standards for human privacy protection. All human biological material, including human cells, should always be handled as potentially infectious using at least Biosafety Level 2 precautions; we recommend that appropriate safety procedures be followed, using the same biosafety protocol used with known infectious material. Viral testing cannot prove the absence of a latent viral genome.

 

Note: Image shown is representative of the cell product described but may not show the actual purchased product.

Additional information

Species/Breed

Tissue

Age

Sex

Catalog Number PBMC-HM-02
Lot Number Included with shipment
Country of Manufacture USA
Quantity 100 x 106 cells/vial           (custom quantities available)
Storage Immediately transfer cells from dry ice to liquid nitrogen upon arrival.
Shipping Info Dry ice; Overnight shipping
Also Known As Blood cells, immune cells, PBMC cells, human mononuclear cells from peripheral blood, HMNC-PB, peripheral mononuclear cells, PMNCs, mononuclear cells, and MNCs.
Product Use This cell product is intended for laboratory research purposes only. Not approved for use in human subjects or for clinical, diagnostic, or therapeutic use in animals or humans.
References Alexovic M, Lindner JR, Bober P, Longuespee R, Sabo J and Davalieva K. Human peripheral blood mononuclear cells: A review of recent proteomic applications. Proteomics. 2022; 22: e2200026. doi: 10.1002/pmic.202200026.

 

Lechner MG, Liebertz DJ and Epstein AL. Characterization of cytokine-induced myeloid-derived suppressor cells from normal human peripheral blood mononuclear cells. The Journal of Immunology. 2010; 185(4): 2273-2284. doi: 10.4049/jimmunol.1000901.

 

Li L, Liu J, Delohery T, Zhang D, Arendt C and Jones C. The effects of teriflunomide on lymphocyte subpopulations in human peripheral blood mononuclear cells in vitro. Journal of Neuroimmunology. 2013; 265(1-2): 82-90. doi: 10.1016/j.jneuroim.2013.10.003.

 

Chan M, Holland EC and Gujral TS. Olverembatinib inhibits SARS-CoV-2-Omicron variant-mediated cytokine release in human peripheral blood mononuclear cells. EMBO Molecular Medicine. 2022; 14: e15919. doi: 10.15252/emmm.202215919.

 

Contact us for the technical documents on this product.

This product is sent on the condition that the customer is responsible for and assumes all risk and responsibility in connection with the receipt, handling, storage, disposal, and use of the JangoCell product including without limitation taking all appropriate safety and handling precautions to minimize health or environmental risk. As a condition of receiving the material, the customer agrees that any activity undertaken with the JangoCell product and any progeny or modifications will be conducted in compliance with all applicable laws, regulations, and guidelines. This product is provided ‘AS IS’ with no representations or warranties whatsoever except as expressly set forth herein and in no event shall JangoCell, its parent company, directors, officers, agents, employees, assigns, successors, and affiliates be liable for indirect, special, incidental, or consequential damages of any kind in connection with or arising out of the customer’s use of the product. Any proposed commercial use is prohibited without a license from JangoCell.

Please see the Terms and Conditions of Sale for further details regarding the use of this product at https://www.jangocell.com/about-us/terms-and-conditions/.

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