Human umbilical vein endothelial cells (HUVECs) serve as a model system for the study of endothelial cell function and disease, and are commonly used in studies involving angiogenesis, homeostasis, inflammatory disorders, atherosclerosis, cancer, and cardiovascular-related diseases.
HUVECs were isolated from the umbilical cord vein of a single donor (female offspring). Cells are cultured, passaged for purity, cryopreserved, and delivered frozen. Each vial contains 1 x 106 cells in 1 mL volume. Cells are characterized by flow cytometry for CD105, CD45, and CD34. HUVECs are negative for mycoplasma, yeast, fungi, and bacteria. HIV-1, HIV-2, and HBV are not detected. Cells are assured to further culture using the protocol provided by JangoCell.
Human Material Precaution
Tissues used for cell isolation were acquired with informed consent and adhere to HIPAA standards for human privacy protection. All human biological material, including human cells, should always be handled as potentially infectious using at least Biosafety Level 2 precautions; we recommend that appropriate safety procedures be followed, using the same biosafety protocol used with known infectious material. Viral testing cannot prove the absence of a latent viral genome.