The SeedEZ cell culture scaffold by Lena Biosciences is a complete 3D cell culture and drug screening system. SeedEZ provides a convenient framework for organ-like tissue models and 3D cell-based assays, as it allows cells to grow in three dimensions as in living tissues.
The SeedEZ scaffold is composed of glass microfibers that are completely inert and transparent. The arrangement of the microfibers creates tiny pores that allow for the passage of nutrients and gases needed for cell survival. The abundance of room in the scaffold enables the cells to divide, branch out, and take on their natural geometry as if they were still inside the human body. In Addition, SeedEZ enables the cells to utilize their cadherin (cell to cell) and integrin (cell to extracellular matrix) receptors which are vital for tissue representative cell behavior, drug responses, and cell therapy outcomes. SeedEZ increases cell survival and metabolism, and allows for the study of cellular communication between different cell types.
SeedEZ is simple to use and works like a piece of paper. Simply pipette one or more cell types into the scaffold, plate in your choice of multi-well plate sizes, and incubate. Assays and imaging are run in situ. SeedEZ supports a wide range of cell types, including primary human neutrophils, T cells, B cells, cancer cells, and normal brain, bone, liver, and lung cells, and extracellular matrices, and is ideally suited for time-course biochemical assaying.
Each order of 24-, 48-, and 96-well plate sizes of SeedEZ contain 24 sterile and ready-to-use scaffolds; orders for 6-well and 12-well plate sizes contain 6 scaffolds per pack. The 5 cm x 10 cm sample sheet (1/pack) can be cut to any size using sterile scissors. Also used with Lena Biosciences Perfused Organ Panel (Cat.#s: LB-2001-48/ LB-2001-12).
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